Glyphosate on your plate

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Any pretext is good to mention what is GLYPHOSATE and why we all should know what it is.

Stephanie Seneff is a senior research scientist at MIT’s Computer Science and Artificial Intelligence Laboratory. She has a bachelor’s degree in biology with a minor in food and nutrition, and a master’s degree, an engineer’s degree, and a PhD in electrical engineering and computer science, all from MIT. For most of her career at MIT she was involved in the development of technology to support natural human-computer communication through spoken language. Since 2010, Dr. Seneff has shifted her research focus toward the effects of drugs, toxic chemicals, and diet on human health and disease, and she has written and spoken extensively, articulating her view on these subjects. She has authored over three dozen peer-reviewed journal papers on topics relating human disease to nutritional deficiencies and toxic exposures. She has focused specifically on the herbicide glyphosate and the mineral sulfur. Dr. Seneff splits her time equally between two homes—one in Kauai, Hawaii, and the other in Winchester, Massachusetts.

Here is a list of fourteen peer-reviewed papers that have been published since 2017 showing glyphosate toxicity in various ways.

1. Robin Mesnage et al. 2017. Multiomics reveal non-alcoholic fatty liver disease in rats following chronic exposure to an ultra-low dose of Roundup herbicide. Scientific reports. www.nature.com/articles/srep39328

2. Daiane Cattani et al. 2017. Developmental exposure to glyphosate-based herbicide and depressive-like behavior in adult offspring: Implication of glutamate excitotoxicity and oxidative stress. Toxicology. www.sciencedirect.com/science/article/pii/S0300483X17301683

3. Stephanie Seneff and Greg Nigh. 2017. Glyphosate and Anencephaly: Death by A Thousand Cuts. Journal of Neurology and Neurobiology. https://sciforschenonline.org/journals/neurology/JNNB-3-140.php

4. Jatinder Pal Kaur Gill et al. 2018. Glyphosate toxicity for animals. Environmental Chemistry Letters. https://link.springer.com/article/10.1007/s10311-017-0689-0

5. Sarath Gunatilake et al. 2019. Glyphosate’s Synergistic Toxicity in Combination with Other Factors as a Cause of Chronic Kidney Disease of Unknown Origin . Int J Environ Res Public Health. https://pubmed.ncbi.nlm.nih.gov/31370256

6. Manon Duforestel et al. 2019. Glyphosate Primes Mammary Cells for Tumorigenesis by Reprogramming the Epigenome in a TET3-Dependent Manner. Frontiers in Genetics. www.frontiersin.org/articles/10.3389/fgene.2019.00885/full

7. Deepika Kubsad et al. 2019. Assessment of Glyphosate Induced epigenetic transgenerational Inheritance of pathologies and sperm epimutations: Generational toxicology. Scientific Reports. www.nature.com/articles/s41598-019-42860-0

8. Antonio Suppa et al. 2020. Roundup causes embryonic development failure and alters metabolic pathways and gut microbiota functionality in non-target species. Microbiome. https://microbiomejournal.biomedcentral.com/articles/10.1186/s40168-020-00943-5

9. Juan P Muñoz et al. 2020. Glyphosate and the key characteristics of an endocrine disruptor: A review. Chemosphere. https://pubmed.ncbi.nlm.nih.gov/33131751

10. Sinji Borges Ferreira Tauhata et al. 2020. The glyphosate controversy: an update. Arq. Inst. Biol. www.scielo.br/j/aib/a/Cb5PGTcqBXw7vKL55cbnJRk/?lang=en

11. Muhammad Irfan Masooda et al. 2021. Environment permissible concentrations of glyphosate in drinking water can influence the fate of neural stem cells from the subventricular zone of the postnatal mouse. Environmental Pollution. www.sciencedirect.com/science/article/abs/pii/S0269749120368688

12. Jianzhong Hu et al. 2021. Low‐dose exposure of glyphosate‐based herbicides disrupt the urine metabolome and its interaction with gut microbiota. Scientific Reports. www.nature.com/articles/s41598-021-82552-2

13. Robin Mesnage et al. 2021. Use of Shotgun Metagenomics and Metabolomics to Evaluate the Impact of Glyphosate or Roundup MON 52276 on the Gut Microbiota and Serum Metabolome of Sprague-Dawley Rats. Environmental Health Perspectives. https://ehp.niehs.nih.gov/doi/full/10.1289/EHP6990

14. Corina Lesseur et al. 2021. Maternal urinary levels of glyphosate during pregnancy and anogenital distance in newborns in a US multicenter pregnancy cohort. Environmental Pollution. https://pubmed.ncbi.nlm.nih.gov/33812205

These preliminary findings partially reproduce our previous results in rodents and suggest that glyphosate is a sex-specific endocrine disruptor with androgenic effects in humans. Given the increasing glyphosate exposures in the US population, larger studies should evaluate potential developmental effects on endocrine and reproductive systems. – Corina Lesseur

We all eat food from supermarkets everyday, we should switch to our own food from the garden free from Roundup or buy only organic food from 100% checked suppliers, if we want to sustain healthy.

*** More details about glyphosate: https://mit.academia.edu/StephanieSeneff